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Mono-functional aminosilanes as primers for peptide functionalization.

Abstract:

When covalently attaching biomolecules to surfaces such as titanium, trifunctional silanes are commonly used as primers to produce surface amine groups. However, these primed surfaces are rarely uniform in structure due to networking of the silane. Mono-functional aminosilanes may result in more uniform structures, although their long-term stability and effect on osteoblast cell responses are possible issues for orthopedic applications. This study examines for the first time the optimization ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1002/jbm.a.32155

Authors


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Institution:
University of Oxford
Department:
Oxford, MSD, NDORMS
Walker, GS More by this author
Scotchford, CA More by this author
Engineering and Physical Sciences Research Council More from this funder
Publisher:
Wiley Publisher's website
Journal:
Journal of biomedical materials research. Part A Journal website
Volume:
90
Issue:
4
Pages:
947-958
Publication date:
2009-09-05
DOI:
EISSN:
1552-4965
ISSN:
1549-3296
URN:
uuid:ff52f8a1-d294-47d1-93cd-0c67d12be12f
Source identifiers:
386677
Local pid:
pubs:386677

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