Journal article
A method for quantifying cellular uptake of fluorescently labeled siRNA.
- Abstract:
-
Efficient intracellular delivery of siRNA is a significant hurdle to its therapeutic success. For biological studies on the efficiency of carrier-mediated uptake of siRNA, quantitative determination of the amount of internalized siRNA is required. In this study, when the apparent uptake of fluorescently labeled siRNA, formulated in different lipo- and polyplexes, was examined using different techniques, major differences were observed. Additional experiments showed that these differences coul...
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- Publisher copy:
- 10.1016/j.jconrel.2010.06.019
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Bibliographic Details
- Journal:
- Journal of controlled release : official journal of the Controlled Release Society
- Volume:
- 148
- Issue:
- 1
- Pages:
- 106-109
- Publication date:
- 2010-11-01
- DOI:
- EISSN:
-
1873-4995
- ISSN:
-
0168-3659
- Source identifiers:
-
345858
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:345858
- UUID:
-
uuid:ff4cbe3d-2573-4789-acf6-ce4b65a9a83b
- Local pid:
- pubs:345858
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2010
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