Journal article icon

Journal article

The role of the GluR-A (GluR1) AMPA receptor subunit in learning and memory.

Abstract:

It is widely believed that synaptic plasticity may provide the neural mechanism that underlies certain kinds of learning and memory in the mammalian brain. The expression of long-term potentiation (LTP) in the hippocampus, an experimental model of synaptic plasticity, requires the GluR-A subunit of the AMPA subtype of glutamate receptor. Genetically modified mice lacking the GluR-A subunit show normal acquisition of the standard, fixed-location, hidden-platform watermaze task, a spatial refer...

Expand abstract
Publication status:
Published

Actions


Access Document


Authors


Sanderson, DJ More by this author
Seeburg, PH More by this author
Sprengel, R More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Expand authors...
Journal:
Progress in brain research
Volume:
169
Pages:
159-178
Publication date:
2008
DOI:
EISSN:
1875-7855
ISSN:
0079-6123
URN:
uuid:ff3db325-4a84-4fb4-a74c-7901c7f53d98
Source identifiers:
2509
Local pid:
pubs:2509

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP