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Plasmodium vivax: isotopic, PicoGreen, and microscopic assays for measuring chloroquine sensitivity in fresh and cryopreserved isolates.

Abstract:

In vitro susceptibility tests provide information on the intrinsic response of Plasmodium vivax to antimalarials, free from confounding factors such as host immunity or relapse. This study examined the utility of radioisotope and PicoGreen assays as alternatives to the traditional microscopic examination for assessing response of P. vivax to antimalarial drugs. There was no significant difference in the mean chloroquine IC(50) of P. vivax (n=40) as determined by the microscopic (33.4 ng/ml), ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.exppara.2006.02.006

Authors


Publisher:
Elsevier
Journal:
Experimental parasitology More from this journal
Volume:
114
Issue:
1
Pages:
34-39
Publication date:
2006-09-01
DOI:
EISSN:
1090-2449
ISSN:
0014-4894
Language:
English
Keywords:
Pubs id:
pubs:19666
UUID:
uuid:ff330440-7866-4cd7-9e0a-0f7e96bc4246
Local pid:
pubs:19666
Source identifiers:
19666
Deposit date:
2012-12-19

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