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The effect of polymorphism at the serotonin transporter gene on decision-making, memory and executive function in ecstasy users and controls.

Abstract:

RATIONALE: 3, 4-Methylenedioxymethamphetamine (MDMA or "ecstasy") is a popular drug of abuse known to result in depletions of the serotonin (5-HT) system. A number of studies have reported that ecstasy users differ from controls on a variety of measures of cognitive function. However, the literature is not consistent and many negative findings were also reported. One reason for such inconsistency might be interindividual variance in vulnerability to the deleterious effects of ecstasy due to ...

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Publication status:
Published

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Publisher copy:
10.1007/s00213-006-0495-z

Authors


Roiser, JP More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Sahakian, BJ More by this author
Journal:
Psychopharmacology
Volume:
188
Issue:
2
Pages:
213-227
Publication date:
2006-10-05
DOI:
EISSN:
1432-2072
ISSN:
0033-3158
URN:
uuid:ff1acc59-6935-4d98-bec3-514a2f603bdc
Source identifiers:
139687
Local pid:
pubs:139687

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