Cytotoxic T lymphocyte responses to human immunodeficiency virus: control and escape.

Journal article

Effective preventive and therapeutic intervention in individuals exposed to or infected with human immunodeficiency virus (HIV) depends, in part, on a clear understanding of the interactions between the virus and those elements of the host immune response which control viral replication. Recent advances have provided compelling evidence that cytotoxic T lymphocytes (CTLs) constitute an essential component of protective antiretroviral immunity. Here, we review briefly the significance of this ...

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Authors: Sewell, A; Price, D; Oxenius, A; Kelleher, A; Phillips, R

• Publication status: Published
• Journal: Stem cells (Dayton, Ohio)
• Volume: 18
• Issue: 4
• Pages: 230-244
• Publication date: 2000-01-01
• DOI: 10.1634/stemcells.18-4-230
• EISSN: 1549-4918
• ISSN: 1066-5099
• Language: English
• Keywords: Disease Models, Animal; Humans; Simian Acquired Immunodeficiency Syndrome; HIV-1; T-Lymphocytes, Cytotoxic; HIV Infections; Animals