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Journal article

Beta burst dynamics in Parkinson’s disease OFF and ON dopaminergic medication

Abstract:

Exaggerated basal ganglia beta activity (13-35 Hz) is commonly found in patients with Parkinson's disease and can be suppressed by dopaminergic medication, with the degree of suppression being correlated with the improvement in motor symptoms. Importantly, beta activity is not continuously elevated, but fluctuates to give beta bursts. The percentage number of longer beta bursts in a given interval is positively correlated with clinical impairment in Parkinson's disease patients. Here we deter...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1093/brain/awx252

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Grant:
Oxford Biomedical Research Centre
Rosetrees Trust More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Brain Journal website
Volume:
140
Issue:
11
Pages:
2968-2981
Publication date:
2017-10-10
Acceptance date:
2017-08-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
Pubs id:
pubs:742280
URN:
uri:ff13713f-d348-4483-a25d-921d9dd07f33
UUID:
uuid:ff13713f-d348-4483-a25d-921d9dd07f33
Local pid:
pubs:742280
Paper number:
11

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