Journal article icon

Journal article

Isolation of new probes from Xq12-->q13: an example of the screening of reference libraries with Alu-PCR products from radiation hybrids.

Abstract:

In order to isolate new probes from the juxtacentromeric region of the long arm of the human X chromosome, we used Alu-mediated polymerase chain reaction (Alu-PCR) products as probes to directly screen a chromosome X-specific gridded cosmid library. These Alu-PCR products were synthesized from radiation hybrids containing the loci DXS159, PGK1, and PGK1P1. This approach allowed us to select 18 cosmids capable of hybridizing with at least two Alu-PCR products. Four cosmids hybridized to more t...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1159/000133383

Authors


Muscatelli, F More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, WTC Human Genetics
Goodfellow, PN More by this author
Hors-Cayla, MC More by this author
Lehrach, H More by this author
Expand authors...
Journal:
Cytogenetics and cell genetics
Volume:
61
Issue:
2
Pages:
109-113
Publication date:
1992-01-05
DOI:
EISSN:
1424-859X
ISSN:
0301-0171
URN:
uuid:ff0cc392-23f1-4467-8233-3d478eb0d03d
Source identifiers:
115650
Local pid:
pubs:115650

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP