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Safety of perioperative aprotinin administration during isolated coronary artery bypass graft surgery: Insights from the ART (Arterial Revascularization Trial)

Abstract:
Background: There is still uncertainty about the safety of aprotinin for coronary artery bypass graft (CABG) surgery. The Arterial Revascularization Trial (ART) was designed to compare survival after bilateral vs single internal thoracic artery grafting. A large proportion of the ART patients (~30%) received perioperative aprotinin. We investigated the association between perioperative Aprotinin administration and short (in-hospital) and long-term outcomes by performing a pos... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1161/JAHA.117.007570

Authors


Benedetto, U More by this author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; CSM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDORMS; CSM
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Surgical Sciences
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Publisher:
American Heart Association Publisher's website
Journal:
Journal of the American Heart Association Journal website
Volume:
7
Issue:
5
Pages:
Article: e007570
Publication date:
2018-03-03
Acceptance date:
2018-01-03
DOI:
ISSN:
2047-9980
Pubs id:
pubs:819291
URN:
uri:fef5d8e4-cfe9-479e-8df2-fd0bec197265
UUID:
uuid:fef5d8e4-cfe9-479e-8df2-fd0bec197265
Local pid:
pubs:819291

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