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Lost but making progress--Where will new analgesic drugs come from?

Abstract:

There is a critical need for effective new pharmacotherapies for pain. The paucity of new drugs successfully reaching the clinic calls for a reassessment of current analgesic drug discovery approaches. Many points early in the discovery process present significant hurdles, making it critical to exploit advances in pain neurobiology to increase the probability of success. In this review, we highlight approaches that are being pursued vigorously by the pain community for drug discovery, includi...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, NDM, Structural Genomics Consortium
Role:
Author
Journal:
Science translational medicine
Volume:
6
Issue:
249
Pages:
249sr3
Chapter number:
ARTN 249sr3
Publication date:
2014-08-05
DOI:
EISSN:
1946-6242
ISSN:
1946-6234
URN:
uuid:fed75459-d0c1-4aa3-8386-c939fd7162f6
Source identifiers:
481476
Local pid:
pubs:481476

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