- Abstract:
-
There is a critical need for effective new pharmacotherapies for pain. The paucity of new drugs successfully reaching the clinic calls for a reassessment of current analgesic drug discovery approaches. Many points early in the discovery process present significant hurdles, making it critical to exploit advances in pain neurobiology to increase the probability of success. In this review, we highlight approaches that are being pursued vigorously by the pain community for drug discovery, includi...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1126/scitranslmed.3008320
-
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- Journal:
- Science translational medicine
- Volume:
- 6
- Issue:
- 249
- Pages:
- 249sr3
- Chapter number:
- ARTN 249sr3
- Publication date:
- 2014-08-05
- DOI:
- EISSN:
-
1946-6242
- ISSN:
-
1946-6234
- URN:
-
uuid:fed75459-d0c1-4aa3-8386-c939fd7162f6
- Source identifiers:
-
481476
- Local pid:
- pubs:481476
- Language:
- English
- Keywords:
- Copyright date:
- 2014
Journal article
Lost but making progress--Where will new analgesic drugs come from?
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