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Structural and functional recovery following limited iatrogenic macular detachment for retinal gene therapy.

Abstract:

Importance

The early decline and recovery of retinal structure and function following iatrogenic macular detachment for retinal gene therapy is not well characterized in those with relatively preserved central visual function. Here, the recovery of retinal structure and function over the first month following iatrogenic retinal detachment for the delivery of adeno-associated viral vector encoding Rab Escort Protein 1 is described as a part of gene therapy for choroideremia.

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Publication status:
Published
Peer review status:
Peer reviewed

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Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
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Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
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Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
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Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
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Funding agency for:
Simunovic, MP
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Funding agency for:
MacLaren, RE
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Funding agency for:
MacLaren, RE
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Publisher:
American Medical Association Publisher's website
Journal:
JAMA Ophthalmology Journal website
Volume:
135
Issue:
3
Pages:
234-241
Publication date:
2017-02-05
Acceptance date:
2016-12-05
DOI:
ISSN:
2168-6173 and 2168-6165
Pubs id:
pubs:675889
URN:
uri:fed4f55f-95c3-40f6-b650-195fa1aef3e0
UUID:
uuid:fed4f55f-95c3-40f6-b650-195fa1aef3e0
Local pid:
pubs:675889
Language:
English
Keywords:

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