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Observation of the unbiased conformers of putative DNA-scaffold ribosugars

Abstract:

The constitution, configuration, and flexibility of the core sugars of DNA molecules alter their function in diverse roles. Conformational itineraries of the ribofuranosides (fs) have long been known to finely determine rates of processing, yet we also know that, strikingly, semifunctional DNAs containing pyranosides (ps) or other configurations can be created, suggesting sufficient but incompletely understood plasticity. The multiple conformers involved in such processes are necessarily infl...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0003-4299-2098
Publisher:
American Chemical Society
Journal:
ACS Central Science More from this journal
Volume:
6
Issue:
2
Pages:
293-303
Publication date:
2020-02-18
Acceptance date:
2020-02-04
DOI:
EISSN:
2374-7951
ISSN:
2374-7943
Pmid:
32123748
Language:
English
Keywords:
Pubs id:
1093632
Local pid:
pubs:1093632
Deposit date:
2020-12-29

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