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Six-year follow-up of impact of co-proxamol withdrawal in England and Wales on prescribing and deaths: time-series study.

Abstract:

BACKGROUND: The analgesic co-proxamol (paracetamol/dextropropoxyphene combination) has been widely involved in fatal poisoning. Concerns about its safety/effectiveness profile and widespread use for suicidal poisoning prompted its withdrawal in the UK in 2005, with partial withdrawal between 2005 and 2007, and full withdrawal in 2008. Our objective in this study was to assess the association between co-proxamol withdrawal and prescribing and deaths in England and Wales in 2005-2010 compared w...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1371/journal.pmed.1001213

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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Role:
Author
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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
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Publisher:
Public Library of Science Publisher's website
Journal:
PLoS medicine Journal website
Volume:
9
Issue:
5
Pages:
Article: e1001213
Publication date:
2012-01-01
DOI:
EISSN:
1549-1676
ISSN:
1549-1277
URN:
uuid:fec94f4e-746f-4b59-bbd4-01b5bd7245bc
Source identifiers:
332816
Local pid:
pubs:332816

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