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Journal article

Commitment to differentiation and cell cycle re-entry are coincident but separable events in the transformation of African trypanosomes from their bloodstream to their insect form.

Abstract:

African trypanosomes undergo extensive changes in cellular morphology, biochemistry and surface antigen expression as they differentiate from their bloodstream form to those forms that colonise the midgut of their tsetse fly vector. If initiated with stumpy-form cells, a non-dividing sub-type of the bloodstream parasite, differentiation and cell cycle re-entry occur synchronously in the population and provide a means to dissect the respective controls of proliferation and transformation. We h...

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Publication status:
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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of cell science More from this journal
Volume:
110 ( Pt 20)
Pages:
2609-2618
Publication date:
1997-10-01
EISSN:
1477-9137
ISSN:
0021-9533
Language:
English
Keywords:
Pubs id:
pubs:31347
UUID:
uuid:fec6f089-0422-4e14-9958-ed8da454f5b7
Local pid:
pubs:31347
Source identifiers:
31347
Deposit date:
2012-12-19

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