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Enzyme kinetics for a two-step enzymic reaction with comparable initial enzyme-substrate ratios

Abstract:

We extend the validity of the quasi-steady state assumption for a model double intermediate enzyme-substrate reaction to include the case where the ratio of initial enzyme to substrate concentration is not necessarily small. Simple analytical solutions are obtained when the reaction rates and the initial substrate concentration satisfy a certain condition. These analytical solutions compare favourably with numerical solutions of the full system of differential equations describing the reactio...

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C. L. Frenzen More by this author
P. K. Maini More by this author
Publication date:
1988
URN:
uuid:fec08026-c477-4aaf-b605-8c267b0d08be
Local pid:
oai:eprints.maths.ox.ac.uk:528

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