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Pallidal activity recorded in patients with implanted electrodes predictively correlates with eventual performance in a timing task.

Abstract:

Here we seek to establish whether there are activities in the human pallidum that may predict a specific aspect of performance, timing. When recording from two patients with Parkinson's disease and primary generalised dystonia following functional neurosurgery we found that the amplitude of oscillatory pallidal activity occurring prior to the completion of a bimanual timing task was strongly correlated with eventual task duration. The frequency of this oscillatory activity was around 25 Hz. W...

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Publication status:
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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Surgical Sciences
Role:
Author
Journal:
Neuroscience letters More from this journal
Volume:
330
Issue:
2
Pages:
188-192
Publication date:
2002-09-01
DOI:
EISSN:
1872-7972
ISSN:
0304-3940
Language:
English
Keywords:
Pubs id:
pubs:70930
UUID:
uuid:feb81f66-d34e-4b3c-a80e-f08311573ca3
Local pid:
pubs:70930
Source identifiers:
70930
Deposit date:
2012-12-19

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