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Longitudinal and cross-sectional analysis of atrophy in Alzheimer's disease: cross-validation of BSI, SIENA and SIENAX.

Abstract:

Brain volume loss (atrophy) is widely used as a marker of disease progression. Atrophy has been measured with a variety of methods, some estimating atrophy rate from two temporally separated scans, and others estimating atrophy state from a single scan. Three popular tools for measuring brain atrophy are BSI and SIENA (rate) and SIENAX (state). Previous papers have shown BSI and SIENA to have similar accuracy, but no work has carefully compared both methods using the same data set. Here we co...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
NeuroImage More from this journal
Volume:
36
Issue:
4
Pages:
1200-1206
Publication date:
2007-07-01
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
Language:
English
Keywords:
Pubs id:
pubs:116763
UUID:
uuid:fe92674f-54c6-4475-87b7-c54494c111f6
Local pid:
pubs:116763
Source identifiers:
116763
Deposit date:
2012-12-19

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