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Journal article

Prevalence of CARD15/NOD2 mutations in Caucasian healthy people.

Abstract:

BACKGROUND: Crohn's disease (CD) has been associated with CARD15/NOD2 mutations in Caucasians. The R702W, G908R, and 1007fs mutations represent 82% of the mutated chromosomes. The relative risk of developing CD in homozygous or compound heterozygous people has been estimated as between 10 and 40 times that of the general population. This high risk may support the opinion that CARD15/NOD2 variants are strong CD risk factors at the individual and population levels. SUBJECTS AND METHODS: The al...

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Publication status:
Published

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Journal:
American journal of gastroenterology More from this journal
Volume:
102
Issue:
6
Pages:
1259-1267
Publication date:
2007-06-01
DOI:
EISSN:
1572-0241
ISSN:
0002-9270
Language:
English
Keywords:
Pubs id:
pubs:135831
UUID:
uuid:fe59de6a-2073-4b84-940d-7475f82bfe2c
Local pid:
pubs:135831
Source identifiers:
135831
Deposit date:
2012-12-19

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