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Multiple Wolbachia strains provide comparative levels of protection against dengue virus infection in Aedes aegypti

Abstract:

The insect bacterium Wolbachia pipientis is being introgressed into Aedes aegypti populations as an intervention against the transmission of medically important arboviruses. Here we compare Ae. aegypti mosquitoes infected with wMelCS or wAlbB to the widely used wMel Wolbachia strain on an Australian nuclear genetic background for their susceptibility to infection by dengue virus (DENV) genotypes spanning all four serotypes. All Wolbachia-infected mosquitoes were more resistant to intrathoraci...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0001-5003-7547
Publisher:
Public Library of Science
Journal:
PLoS Pathogens More from this journal
Volume:
16
Issue:
4
Article number:
e1008433
Publication date:
2020-04-13
Acceptance date:
2020-02-25
DOI:
EISSN:
1553-7374
ISSN:
1553-7366
Pmid:
32282862
Language:
English
Keywords:
Pubs id:
1100446
Local pid:
pubs:1100446
Deposit date:
2020-06-19

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