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Spatiotemporal modelling of CheY complexes in escherichia coli chemotaxis

Abstract:

The chemotaxis pathway of Escherichia coli is one of the best studied and modelled biological signalling pathways. Here we extend existing modelling approaches by explicitly including a description of the formation and subcellular localization of intermediary complexes in the phosphotransfer pathway. The inclusion of these complexes shows that only about 60% of the total output response regulator (CheY) is uncomplexed at any moment and hence free to interact with its target, the flagellar mot...

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M. J. Tindall More by this author
S. L. Porter More by this author
G H Wadhams More by this author
P. K. Maini More by this author
J. P. Armitage More by this author
Publication date:
2009
URN:
uuid:fe53a109-0656-4bf0-84a0-0a1a8a769cbe
Local pid:
oai:eprints.maths.ox.ac.uk:849

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