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Transneuronal retrograde degeneration of retinal ganglion cells and optic tract in hemianopic monkeys and humans.

Abstract:

Transneuronal retrograde degeneration of retinal ganglion cells after removal of primary visual cortex (area V1) is well established by quantitative neurohistological analysis of the ganglion cell layer in monkeys, but remains controversial in human patients. Therefore, we first histologically examined retinal degeneration in sectioned archived retinae of 26 macaque monkeys with unilateral V1 ablation and post-surgical survival times ranging from 3 months to 14.3 years. In addition, the cross...

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Publication status:
Published

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Publisher copy:
10.1093/brain/awr125

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Psychology
Role:
Author
Journal:
Brain : a journal of neurology
Volume:
134
Issue:
Pt 7
Pages:
2149-2157
Publication date:
2011-07-05
DOI:
EISSN:
1460-2156
ISSN:
0006-8950
URN:
uuid:fe4900af-63a2-420a-96a5-f6d66c68a09b
Source identifiers:
163930
Local pid:
pubs:163930

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