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A coalescent-based method for detecting and estimating recombination from gene sequences.

Abstract:

Determining the amount of recombination in the genealogical history of a sample of genes is important to both evolutionary biology and medical population genetics. However, recurrent mutation can produce patterns of genetic diversity similar to those generated by recombination and can bias estimates of the population recombination rate. Hudson 2001 has suggested an approximate-likelihood method based on coalescent theory to estimate the population recombination rate, 4N(e)r, under an infinite...

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Publication status:
Published

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Authors


Awadalla, P More by this author
Fearnhead, P More by this author
Journal:
Genetics
Volume:
160
Issue:
3
Pages:
1231-1241
Publication date:
2002-03-05
EISSN:
1943-2631
ISSN:
0016-6731
URN:
uuid:fe3aed38-f72c-457b-8f61-0ac1d568d4ed
Source identifiers:
103156
Local pid:
pubs:103156

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