- Abstract:
-
The age-adjusted risk of prostate cancer (PC) has increased in Singapore since 1968. We investigated the relationship between polymorphisms in four genes, androgen receptor (AR), prostate-specific antigen (PSA), 5alpha-reductase type II (SRD5A2) and cytochrome P450c17alpha (CYP17) and PC and benign prostatic hyperplasia (BPH). Men with shorter CAG repeats in AR and above 69 years at diagnosis showed a trend of decreased PC risk (OR=0.28, 95% CI=0.08-1.03; p=0.05). Shorter CAG repeats and non-...
Expand abstract - Publisher copy:
- 10.1016/j.canlet.2008.04.009
-
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- Journal:
- Cancer letters
- Volume:
- 268
- Issue:
- 2
- Pages:
- 340-347
- Publication date:
- 2008-09-05
- DOI:
- EISSN:
-
1872-7980
- ISSN:
-
0304-3835
- URN:
-
uuid:fe1a7c8c-4e4f-4a5b-8474-7e033d6fb403
- Source identifiers:
-
134343
- Local pid:
- pubs:134343
- Copyright date:
- 2008
Journal article
Shorter CAG repeats in androgen receptor and non-GG genotypes in prostate-specific antigen loci are associated with decreased risk of benign prostatic hyperplasia and prostate cancer.
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