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A quantitative trait locus for SBP maps near KCNB1 and PTGIS in a population isolate.

Abstract:

BACKGROUND: Population isolates are characterized by simplified genetic background and as such present promising opportunities for studying complex diseases. We performed a genome-wide linkage analysis for systolic (SBP) and diastolic blood pressure (DBP) followed up by the association analysis in the Croatian isolated island of Vis, where a very high prevalence of hypertension was reported (75%). METHODS: Variance-components linkage analysis was used to map quantitative trait loci (QTL) for ...

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Publication status:
Published

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Publisher copy:
10.1038/ajh.2009.46

Authors


Barbalić, M More by this author
Narancić, NS More by this author
Skarić-Jurić, T More by this author
Salihović, MP More by this author
Klarić, IM More by this author
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Journal:
American journal of hypertension
Volume:
22
Issue:
6
Pages:
663-668
Publication date:
2009-06-05
DOI:
EISSN:
1941-7225
ISSN:
0895-7061
URN:
uuid:fdf133cf-cb73-43e1-add3-278f5ed36776
Source identifiers:
105203
Local pid:
pubs:105203

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