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Propylthiouracil and carbimazole associated-antineutrophil cytoplasmic antibodies (ANCA) in patients with Graves' disease.

Abstract:

OBJECTIVE: Propylthiouracil treatment of Graves' disease has been postulated to provoke antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis. We aimed to investigate whether carbimazole therapy was also associated with increased risk of ANCA. DESIGN: The occurrence of ANCA and the relationship to thionamide treatment was investigated in a cross-sectional study in a consecutive series of 407 patients' with Graves' disease, 200 with Hashimoto's thyroiditis and 649 normal euthyroid s...

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Authors


Allahabadia, A More by this author
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Journal:
Clinical endocrinology
Volume:
60
Issue:
6
Pages:
671-675
Publication date:
2004-06-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:fdb68cf9-8668-4986-ba95-f043f84c5cb2
Source identifiers:
176344
Local pid:
pubs:176344

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