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Cannabinoid 1 receptors are expressed in nociceptive primary sensory neurons.

Abstract:

Expression of cannabinoid 1 (CB1) and vanilloid 1 (VR1) receptor proteins was studied in adult, cultured rat dorsal root ganglion neurons. Immunostaining of CB1 receptors alone produced labelling in 57+/-2% of the cultured dorsal root ganglion neurons (n=3 cultures). The area of the labelled cells was between 200 and 800 microm(2) with an average of 527+/-68 microm(2). VR1 immunolabelling revealed immunopositivity in 42+/-6% of the total population of dorsal root ganglion neurons. Cells showi...

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
Neuroscience More from this journal
Volume:
100
Issue:
4
Pages:
685-688
Publication date:
2000-01-01
DOI:
EISSN:
1873-7544
ISSN:
0306-4522
Language:
English
Keywords:
Pubs id:
pubs:329227
UUID:
uuid:fd9f5bc3-e80d-4ee5-a591-1356cab293aa
Local pid:
pubs:329227
Source identifiers:
329227
Deposit date:
2013-11-16

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