Journal article icon

Journal article

Relationship between changes in thymic emigrants and cell-associated HIV-1 DNA in HIV-1-infected children initiating antiretroviral therapy.

Abstract:

OBJECTIVES AND METHODS: To investigate the relationship between cell-associated HIV-1 dynamics and recent thymic T-cell emigrants, HIV-1 DNA and T-cell receptor rearrangement excision circles (TREC, a marker of recent thymic emigrants) were measured in peripheral blood mononuclear cells in 181 samples from 33 HIV-1-infected children followed for 96 weeks after antiretroviral therapy (ART) initiation. RESULTS: At baseline, HIV-1 DNA was higher in children with higher TREC (P=0.02) and was not...

Expand abstract
Publication status:
Published

Actions


Authors


De Rossi, A More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
De Forni, D More by this author
Journal:
Antiviral therapy
Volume:
10
Issue:
1
Pages:
63-71
Publication date:
2005
EISSN:
2040-2058
ISSN:
1359-6535
URN:
uuid:fd9e22cb-2593-4a94-a038-0eab48078c75
Source identifiers:
423377
Local pid:
pubs:423377

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP