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Comparison of the risk of fatal coronary heart disease in treated xanthomatous and non-xanthomatous heterozygous familial hypercholesterolaemia: a prospective registry study.

Abstract:

BACKGROUND: A clinical diagnosis of familial hypercholesterolaemia (FH) is often made in the absence of tendon xanthomata (TX), which are not usually present before the fourth decade of life. The prognosis of treated non-xanthomatous (TX-) FH is uncertain and the objective of this study was to compare mortality from coronary heart disease (CHD) in patients with treated TX+ (definite) and TX- (possible) heterozygous FH. METHODS: A diagnosis of definite or possible FH was based on raised chole...

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Institution:
University of Oxford
Department:
Oxford
Role:
Author
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Journal:
Atherosclerosis
Volume:
170
Issue:
1
Pages:
73-78
Publication date:
2003-09-05
DOI:
EISSN:
1879-1484
ISSN:
0021-9150
URN:
uuid:fd945f5f-4164-455e-a38c-a0fbc0ba3019
Source identifiers:
72767
Local pid:
pubs:72767

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