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Intracellular Ca2+ release and synaptic plasticity: A tale of many stores

Abstract:

Ca2+ is an essential trigger for most forms of synaptic plasticity. Ca2+ signaling occurs not only by Ca2+ entry via plasma membrane channels but also via Ca2+ signals generated by intracellular organelles. These organelles, by dynamically regulating the spatial and temporal extent of Ca2+ elevations within neurons, play a pivotal role in determining the downstream consequences of neural signaling on synaptic function. Here, we review the role of three major intracellular stores: the endoplas...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1177/1073858418785334

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
Publisher:
SAGE Publications Publisher's website
Journal:
Neuroscientist Journal website
Volume:
25
Issue:
3
Pages:
208-226
Publication date:
2018-07-17
Acceptance date:
2018-06-08
DOI:
EISSN:
1089-4098
ISSN:
1073-8584
Pubs id:
pubs:856586
URN:
uri:fd90d492-e215-4dc9-91d5-8ba51f481add
UUID:
uuid:fd90d492-e215-4dc9-91d5-8ba51f481add
Local pid:
pubs:856586

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