- Abstract:
-
Nanoscale spacing between the plasma membrane and the underlying cortical actin cytoskeleton profoundly modulates cellular morphology, mechanics, and function. Measuring this distance has been a key challenge in cell biology. Current methods for dissecting the nanoscale spacing either limit themselves to complex survey design using fixed samples or rely on diffraction-limited fluorescence imaging whose spatial resolution is insufficient to quantify distances on the nanoscale. Using dual-color...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 3.0MB)
-
- Publisher copy:
- 10.1088/1361-6463/aa52a1
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- Publisher:
- Institute of Physics Publisher's website
- Journal:
- Journal of Physics D: Applied Physics Journal website
- Volume:
- 50
- Issue:
- 6
- Publication date:
- 2017-01-05
- Acceptance date:
- 2016-12-08
- DOI:
- ISSN:
-
1361-6463 and 0022-3727
- Pubs id:
-
pubs:679621
- URN:
-
uri:fd858caa-b120-44d4-97c0-87843640d04d
- UUID:
-
uuid:fd858caa-b120-44d4-97c0-87843640d04d
- Local pid:
- pubs:679621
- Copyright holder:
- IOP Publishing Ltd
- Copyright date:
- 2017
- Notes:
- © 2017 IOP Publishing Ltd. Printed in the UK. Original content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI.
Journal article
Dissecting the actin cortex density and membrane-cortex distance in living cells by super-resolution microscopy
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