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Secretion of adipokines by human adipose tissue in vivo: partitioning between capillary and lymphatic transport.

Abstract:

Peptides secreted by adipose tissue (adipokines) may enter blood via capillaries or lymph. The relative importance of these pathways for a given adipokine might influence its biological effects. Because this has not been studied in any species, we measured the concentrations of seven adipokines and eight nonsecreted proteins in afferent peripheral lymph and venous plasma from 12 healthy men. Data for nonsecreted proteins were used to derive indices of microvascular permeability, which in conj...

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Publication status:
Published

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Publisher copy:
10.1152/ajpendo.00058.2011

Authors


Journal:
American journal of physiology. Endocrinology and metabolism More from this journal
Volume:
301
Issue:
4
Pages:
E659-E667
Publication date:
2011-10-01
DOI:
EISSN:
1522-1555
ISSN:
0193-1849
Language:
English
Keywords:
Pubs id:
pubs:166465
UUID:
uuid:fd7945bd-5ef8-45af-a8bf-a6c8135f0042
Local pid:
pubs:166465
Source identifiers:
166465
Deposit date:
2012-12-19

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