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Mosquito mortality and the evolution of malaria virulence.

Abstract:

Several laboratory studies of malaria parasites (Plasmodium sp.) and some field observations suggest that parasite virulence, defined as the harm a parasite causes to its vertebrate host, is positively correlated with transmission. Given this advantage, what limits the continual evolution of higher parasite virulence? One possibility is that while more virulent strains are more infectious, they are also more lethal to mosquitoes. In this study, we tested whether the virulence of the rodent ma...

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Publication status:
Published

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Authors


Ferguson, HM More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Journal:
Evolution; international journal of organic evolution
Volume:
57
Issue:
12
Pages:
2792-2804
Publication date:
2003-12-05
DOI:
EISSN:
1558-5646
ISSN:
0014-3820
URN:
uuid:fd76242c-07ab-49d7-8fd7-3cb801509f1c
Source identifiers:
90487
Local pid:
pubs:90487

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