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A qualitative and quantitative assessment of fundus autofluorescence patterns in patients with choroideremia

Abstract:

PURPOSE.We set out to characterize the pattern of fundus autofluorescence (AF) loss in choroideremia (CHM) patients of varying ages and disease severity in order to determine the average rate of progression of this potential disease biomarker.METHODS.Fifty consecutive CHM patients (100 eyes) attending outpatient clinics at Oxford Eye Hospital underwent analysis with the Heidelberg OCT Spectralis with autofluorescence capabilities.The area of residual AF was traced using Heidelberg Eye Explore...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1167/iovs.15-18362

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Department:
Oxford, MSD, Clinical Neurosciences
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Author
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Department:
Oxford, MSD, Clinical Neurosciences
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Author
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Department:
Oxford, MSD, Clinical Neurosciences
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Author
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Department:
Oxford, MSD, Clinical Neurosciences
Role:
Author
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National Institute for Health Research Oxford Biomedical Research Centre More from this funder
Fight for Sight More from this funder
Publisher:
Association for Research in Vision and Ophthalmology Publisher's website
Journal:
Investigative Ophthalmology and Visual Science Journal website
Volume:
57
Issue:
10
Pages:
4498-4503
Publication date:
2016-08-01
DOI:
EISSN:
1552-5783
ISSN:
0146-0404
Pubs id:
pubs:642701
URN:
uri:fd6f6a50-96d0-4cb7-a5b5-5550ef1c3463
UUID:
uuid:fd6f6a50-96d0-4cb7-a5b5-5550ef1c3463
Local pid:
pubs:642701
Paper number:
10

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