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Journal article

High prevalence of individuals with low concentration of fetal hemoglobin in F-cells in sickle cell anemia in Tanzania.

Abstract:

Sickle cell anemia (SCA) has a high prevalence in Sub-Saharan Africa, with up to 11,000 births of SCA individuals occurring in Tanzania annually [1]. Fetal hemoglobin (HbF) is one of the most important factors influencing the disease severity. In adults, HbF expression is restricted to a subset of red blood cells (RBCs) called F-cells. Although high HbF is associated with mild disease, there are reports of severe disease occurring in individuals with high HbF levels. One of the factors that a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1002/ajh.24390

Authors


Publisher:
Wiley
Journal:
American Journal of Hematology More from this journal
Publication date:
2016-05-01
Acceptance date:
2016-04-13
DOI:
EISSN:
1096-8652
ISSN:
0361-8609
Language:
English
Pubs id:
pubs:617609
UUID:
uuid:fd6a8cf7-f47a-4952-9bb6-e5aa4e9762bb
Local pid:
pubs:617609
Source identifiers:
617609
Deposit date:
2016-06-24

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