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A single photon emission computerised tomography study of regional brain function in elderly patients with major depression and with Alzheimer-type dementia.

Abstract:

The uptake, at rest, of 99mTc-exametazime into different brain regions was compared using SPECT for 20 elderly subjects with major depressive disorder, 20 with Alzheimer-type dementia, and 30 age-matched normal volunteers. Uptake was referred to calcarine-occipital cortex as a reference sensory area. Cross-sectional differences between the three groups were highly statistically significant, but reflected primarily the reductions in cortical uptake in the Alzheimer group. A detailed comparison...

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Publisher copy:
10.1192/bjp.163.2.155

Authors


Curran, SM More by this author
Murray, CM More by this author
Van Beck, M More by this author
Dougall, N More by this author
O'Carroll, RE More by this author
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Journal:
The British journal of psychiatry : the journal of mental science
Volume:
163
Issue:
2
Pages:
155-165
Publication date:
1993-08-05
DOI:
EISSN:
1472-1465
ISSN:
0007-1250
URN:
uuid:fd694ef4-6a05-4150-8e5e-4085704c87b6
Source identifiers:
139285
Local pid:
pubs:139285

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