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Identification of stage-regulated and differentiation-enriched transcripts during transformation of the African trypanosome from its bloodstream to procyclic form.

Abstract:

Trypanosoma brucei undergoes dramatic stage-specific changes in surface antigen expression, metabolic development, cellular morphogenesis and cell-cycle control. These events can be studied in detail during the transition between the bloodstream stumpy stage and the tsetse fly midgut procyclic form. This differentiation can be induced in vitro, is synchronous in the population and there are abundant markers for stage-regulated and differentiation events. We have used this differentiation syst...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Role:
Author
Journal:
Molecular and biochemical parasitology
Volume:
95
Issue:
1
Pages:
81-95
Publication date:
1998-09-05
DOI:
EISSN:
1872-9428
ISSN:
0166-6851
URN:
uuid:fd634c23-459b-42c7-a5a7-d37e08d3aa35
Source identifiers:
21245
Local pid:
pubs:21245

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