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Journal article

Vulnerability to Alzheimer's pathology in neocortex: The roles of plasticity and columnar organization

Abstract:

Two principal findings in the Pearson et al. paper [73] are commented on here. The first is the regional selectivity within the cerebrum of neurofibrillary tangle (NFT) formation in Alzheimer's disease (AD) which targets association cortex and the primary olfactory cortex alone among regions of primary sensory cortex. The second finding is the clustering of NFT in columns of supra- and infra-granular layers of association cortex. We review recent evidence confirming these findings and comment...

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Publisher:
IOS Press
Pages:
79-89
Publication date:
2006-07-01
Source identifiers:
415354
Language:
English
Keywords:
Pubs id:
pubs:415354
UUID:
uuid:fd5fb33f-ba0a-4aba-b852-5df135adc410
Local pid:
pubs:415354
Deposit date:
2013-11-17

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