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Correction of both prothrombin time and primary haemostasis by recombinant factor VII during therapeutic alcohol injection of hepatocellular cancer in liver cirrhosis.

Abstract:

We evaluated the efficacy of recombinant factor VII to correct impaired haemostasis in a patient with liver cirrhosis requiring an invasive procedure. A test intravenous bolus of 80 microg/kg of recombinant factor VII was given to a Jehovah's Witness, with a solitary 4.4-cm hepatocellular carcinoma and underlying hepatitis C virus cirrhosis, in an attempt to correct his haemostatic disorders and safely inject the tumour with alcohol. An extensive portal block had precluded consideration of li...

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Publication status:
Published

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Authors


Papatheodoridis, GV More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Experimental Medicine Division, Clinical Medicine
Burroughs, AK More by this author
Journal:
Journal of hepatology
Volume:
31
Issue:
4
Pages:
747-750
Publication date:
1999-10-05
DOI:
EISSN:
1600-0641
ISSN:
0168-8278
URN:
uuid:fd5bc95a-420d-49e4-9e05-24d95e810301
Source identifiers:
66414
Local pid:
pubs:66414

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