Journal article icon

Journal article

Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells.

Abstract:

The nuclear lamina forms a protein mesh that underlies the nuclear membrane. In most mammalian cells it contains the intermediate filament proteins, lamins A, B and C. As their name indicates, lamins are generally thought to be confined to the nuclear periphery. We now show that they also form part of a diffuse skeleton that ramifies throughout the interior of the nucleus. Unlike their peripheral counterparts, these internal lamins are buried in dense chromatin and so are inaccessible to anti...

Expand abstract
Publication status:
Published

Actions


Authors


Sasseville, AM More by this author
Raymond, Y More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Journal:
Journal of cell science
Volume:
108 ( Pt 2)
Pages:
635-644
Publication date:
1995-02-05
EISSN:
1477-9137
ISSN:
0021-9533
URN:
uuid:fd50ca53-2711-4939-b2e6-066c21984426
Source identifiers:
25129
Local pid:
pubs:25129

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP