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Journal article

Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells.

Abstract:

The nuclear lamina forms a protein mesh that underlies the nuclear membrane. In most mammalian cells it contains the intermediate filament proteins, lamins A, B and C. As their name indicates, lamins are generally thought to be confined to the nuclear periphery. We now show that they also form part of a diffuse skeleton that ramifies throughout the interior of the nucleus. Unlike their peripheral counterparts, these internal lamins are buried in dense chromatin and so are inaccessible to anti...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
Journal:
Journal of cell science More from this journal
Volume:
108 ( Pt 2)
Pages:
635-644
Publication date:
1995-02-01
EISSN:
1477-9137
ISSN:
0021-9533
Language:
English
Keywords:
Pubs id:
pubs:25129
UUID:
uuid:fd50ca53-2711-4939-b2e6-066c21984426
Local pid:
pubs:25129
Source identifiers:
25129
Deposit date:
2012-12-19

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