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Class II major histocompatibility complex-restricted T cell function in CD4-deficient mice.

Abstract:

Previously, we and others have demonstrated that CD4-deficient mice have a normal number of T cells and B cells with a significant population of CD4-8-TcR alpha beta+ T cells. Surprisingly, however, these mice lacking CD4 show in vivo immunoglobulin isotype class switching from IgM to IgG in response to sheep erythrocytes and vesicular stomatitis virus. In this study we have depleted various subpopulations of T cells in vivo and shown that the population of CD4-8-TcR alpha beta+ T cells is re...

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Publication status:
Published

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Publisher copy:
10.1002/eji.1830240942

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Journal:
European journal of immunology More from this journal
Volume:
24
Issue:
9
Pages:
2213-2218
Publication date:
1994-09-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Language:
English
Keywords:
Pubs id:
pubs:404105
UUID:
uuid:fd45febf-812e-4afd-9916-e4dc5e9955b9
Local pid:
pubs:404105
Source identifiers:
404105
Deposit date:
2014-06-17

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