- Abstract:
-
Operator control of cell/matrix density of plastically compressed collagen hydrogel scaffolds critically depends on reproducibly limiting the extent of scaffold compaction, as fluid expulsion. A functional model of the compression process is presented, based on the idea that the main fluid-leaving surface (FLS) behaves as an ultrafiltration membrane, allowing fluid (water) out but retaining collagen fibrils to form a cake. We hypothesize that accumulation of collagen at the FLS produces aniso...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1002/term.343
-
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- Journal:
- Journal of tissue engineering and regenerative medicine
- Volume:
- 5
- Issue:
- 7
- Pages:
- 505-519
- Publication date:
- 2011-07-05
- DOI:
- EISSN:
-
1932-7005
- ISSN:
-
1932-6254
- URN:
-
uuid:fd4586fd-d6c0-4ee3-b378-6fbfe52c8335
- Source identifiers:
-
166599
- Local pid:
- pubs:166599
- Language:
- English
- Keywords:
- Copyright date:
- 2011
Journal article
Mechanisms of structure generation during plastic compression of nanofibrillar collagen hydrogel scaffolds: towards engineering of collagen.
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