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Journal article

Pancreatic ectopic fat is characterized by adipocyte infiltration and altered lipid composition.

Abstract:

OBJECTIVE: Sustained exposure to lipids is deleterious for pancreatic islet function. This could be mediated through increased pancreatic fat following increased dietary fat and in obesity, which has implications for the onset of type 2 diabetes. The aims of this study were to determine changes in extent and composition of pancreatic, hepatic, and visceral fat in mice fed a high-fat diet (HFD, 40% by weight) compared with a control diet (5% fat) of similar fatty acid composition, and to comp...

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Publication status:
Published

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Publisher copy:
10.1038/oby.2007.110

Authors


Pinnick, KE More by this author
Collins, SC More by this author
Gauguier, D More by this author
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Journal:
Obesity (Silver Spring, Md.)
Volume:
16
Issue:
3
Pages:
522-530
Publication date:
2008-03-05
DOI:
EISSN:
1930-739X
ISSN:
1930-7381
URN:
uuid:fd100d68-cc9d-41a3-b0ae-b12550dff04b
Source identifiers:
17946
Local pid:
pubs:17946

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