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Journal article

Confounding of cerebral blood flow velocity by blood pressure during breath-holding or hyperventilation in TIA or stroke

Abstract:

Background and Purpose: Breath-holding (BH) and hyperventilation (HV) are used to assess abnormal cerebrovascular reactivity (CVR), often in relation to severity of small vessel disease and risk of stroke with carotid stenosis, but responses may be confounded by blood pressure (BP) changes. We compared effects of BP and end-tidal CO2 (etCO2) on middle cerebral artery mean flow velocity (MFV) in consecutive TIA and minor stroke patients.

Methods: In ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1161/STROKEAHA.119.027829

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
Wadham College
Role:
Author
ORCID:
0000-0002-0630-8204
More from this funder
Name:
Wellcome Trust
Grant:
206589/Z/17/Z
More from this funder
Name:
British Heart Foundation
Grant:
PG/16/38/32080
Publisher:
American Heart Association
Journal:
Stroke More from this journal
Volume:
51
Issue:
2
Pages:
468–474
Publication date:
2019-12-30
Acceptance date:
2019-11-15
DOI:
EISSN:
1524-4628
ISSN:
0039-2499
Pubs id:
pubs:1077593
UUID:
uuid:fd0e9206-ad16-4966-9ccc-ca43e3921528
Local pid:
pubs:1077593
Source identifiers:
1077593
Deposit date:
2019-12-13

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