Expression and mutagenesis of bacteriorhodopsin an integral membrane protein
Although integral membrane proteins represent nearly a quarter of the genes present in both prokaryotes and eukaryotes, progress in this area of research is often hindered due to the nature of their hydrophobic environment. Elucidating the folding pathway of these proteins is essential to understand many membrane mediated biological processes such as signal transduction, ion transport and chemotaxis.
The wealth of structural and genetic information on bacteriorhodpsin renders it an ...Expand abstract
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- University of Oxford
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- Sidhu, Inderjit Kaur
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