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Dengue virus infections and maternal antibody decay in a prospective birth cohort study of Vietnamese infants

Abstract:

Dengue hemorrhagic fever can occur in primary dengue virus (DENV) infection of infants. The decay of maternally derived DENV immunoglobulin (Ig) G and the incidence of DENV infection were determined in a prospectively studied cohort of 1244 Vietnamese infants. Higher concentrations of total IgG and DENV-reactive IgG were found in cord plasma relative to maternal plasma. Maternally derived DENV-neutralizing and E protein–reactive IgG titers declined to below me...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1086/648407

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Oxford college:
St Catherine's College
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Publisher:
Oxford University Press
Journal:
Journal of Infectious Diseases More from this journal
Volume:
200
Issue:
12
Pages:
1893-1900
Publication date:
2009-12-15
Acceptance date:
2009-07-29
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
Pmid:
19911991
Language:
English
Keywords:
Pubs id:
pubs:34972
UUID:
uuid:fcfda7ea-cd30-43ea-b70b-d2bbacb97e8d
Local pid:
pubs:34972
Source identifiers:
34972
Deposit date:
2017-07-19

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