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Altitude sickness in climbers and efficacy of NSAIDs trial (ASCENT): Randomized, controlled trial of ibuprofen versus placebo for prevention of altitude illness

Abstract:

Objective: To study the effectiveness of ibuprofen versus placebo in preventing acute mountain sickness (AMS) and high altitude headache (HAH). Methods: Double-blind, randomized, placebo-controlled trial. Results: Two hundred ninety-four healthy Western trekkers were recruited on the Everest approach at 4280 m or 4358 m and randomly assigned to receive either 600 mg of ibuprofen or placebo 3 times daily before and during ascent to 4928 m. One hundred eighty-three of 294 participants completed...

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Publisher copy:
10.1016/j.wem.2012.08.001

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Journal:
Wilderness and Environmental Medicine
Volume:
23
Issue:
4
Pages:
307-315
Publication date:
2012-12-05
DOI:
ISSN:
1080-6032
URN:
uuid:fcecdf9d-180b-480d-9f6b-b820291ad93b
Source identifiers:
366747
Local pid:
pubs:366747

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