Journal article icon

Journal article

African HIV/AIDS trials are more likely to report adequate allocation concealment and random generation than North American trials.

Abstract:

BACKGROUND: Adherence to good methodological quality is necessary to minimise bias in randomised conrolled trials (RCTs). Specific trial characteristics are associated with better trial quality, but no studies to date are specific to HIV/AIDS or African trials. We postulated that location may negatively impact on trial quality in regions where resources are scarce. METHODS: 1) To compare the methodological quality of all HIV/AIDS RCTs conducted in Africa with a random sample of similar trial...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0003491

Authors


More by this author
Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
Publisher:
Public Library of Science
Journal:
PloS one More from this journal
Volume:
3
Issue:
10
Article number:
e3491
Publication date:
2008-01-01
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Language:
English
Keywords:
Pubs id:
pubs:79066
UUID:
uuid:fceb95da-741a-4220-8cff-59f8867dcb6d
Local pid:
pubs:79066
Source identifiers:
79066
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP