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Journal article

Epiregulin (EREG) variation is associated with susceptibility to tuberculosis.

Abstract:

Although host genetics influences susceptibility to Mycobacterium tuberculosis, the human genes regulating pathogenesis remain largely unknown. We used M. tuberculosis-stimulated macrophage gene expression profiling in conjunction with a case-control genetic association study to discover epiregulin (EREG), as a novel candidate tuberculosis (TB) susceptibility gene. Using a genome-wide association study dataset, we found that among the 21 genes with greater than 50-fold induction, EREG had the...

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Publication status:
Published

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Publisher copy:
10.1038/gene.2011.83

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Journal:
Genes and immunity More from this journal
Volume:
13
Issue:
3
Pages:
275-281
Publication date:
2012-04-01
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Language:
English
Keywords:
Pubs id:
pubs:221326
UUID:
uuid:fce6d3be-5b2b-49c4-9162-0e5f61795240
Local pid:
pubs:221326
Source identifiers:
221326
Deposit date:
2012-12-19

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