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Journal article

Evolutionary convergence of alternative splicing in ion channels.

Abstract:

In Drosophila melanogaster and humans, members of three different ion-channel gene families share tandem exon duplications, which are alternatively spliced. In this article, I demonstrate that the duplication events that give rise to these mutually exclusive exons are unlikely to be ancestral but have probably occurred independently in different lineages. These events provide remarkable examples of evolutionary convergence in alternative splicing. The result has important implications for the...

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Publication status:
Published

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Publisher copy:
10.1016/j.tig.2004.02.001

Authors


Copley, RR More by this author
Journal:
Trends in genetics : TIG
Volume:
20
Issue:
4
Pages:
171-176
Publication date:
2004-04-05
DOI:
ISSN:
0168-9525
URN:
uuid:fce47cf8-440b-49e9-869c-cc5aa68f01e1
Source identifiers:
54036
Local pid:
pubs:54036

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