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Journal article

The high-risk corneal regraft model: a justification for tissue matching in humans.

Abstract:

Models of high-risk corneal graft rejection involve neovascularization induced via innate immune responses, e.g., suture-mediated trauma. We describe a model of high-risk corneal graft rejection using corneal graft donor-recipient pairing based on a single-antigen disparity. Donor corneas from transgenic mice on B10.BR (H-2k ) background, in which hen-egg lysozyme (HEL) as a membrane-bound antigen (mHEL) was expressed under the major histocompatibility complex (MHC) class I promoter (KLK-mHEL...

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Publication status:
Published

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Publisher copy:
10.1111/tri.12055

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, CCMP, Molecular Medicine
Role:
Author
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Journal:
Transplant international : official journal of the European Society for Organ Transplantation
Volume:
26
Issue:
4
Pages:
453-461
Publication date:
2013-04-05
DOI:
EISSN:
1432-2277
ISSN:
0934-0874
URN:
uuid:fcdcde3e-c9e5-411c-ba82-88f127b40953
Source identifiers:
384096
Local pid:
pubs:384096

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